Laktát

Tvorba

• Ve svalovině
• Erytrocyty

Zvýšené hladiny

• Strenuous exercise
• Heart failure
• Severe infection (sepsis)
• Shock s hypoxií tkání
• Liver is severely damaged or diseased
• Liver normally breaks down lactic acid
• Severe lung disease or respiratory failure
• Pulmonary edema
• Severe anemia
• Accumulates in the body if glucose cannot be completely broken down due to lack of oxygen or insulin
• Uncontrolled diabetes
• Leukemia
• AIDS
• Glycogen storage diseases
• Glucose-6-phosphatase deficiency
• Drugs and toxins
• Salicylates
• Cyanide
• Methanol
• Metformin
• Inherited metabolic and mitochondrial diseases
• Muscular dystrophy
• Affect normal ATP production

Lactic acidosis

• život ohrožující stav
• Riziko vzniku
• Terapie metforminem a sulfonylureou when heart or kidney failure or a severe infection is also present
• Symptomy
• Rapid breathing
• Excessive sweating
• Cool and clammy skin
• Sweet-smelling breath
• Belly pain, nausea or vomiting
• Confusion, and coma