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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
Deprecated: Function split() is deprecated in /home/users/dana/medicinman.cz/web/csf/kf.inc.php on line 67
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Siccaprotect
- V 1 ml očních kapek
- Dexpanthenolum 30 mg
- Alcohol polyvinylicus 14 mg
- 1 ml = cca 30 kapek
- Seznam pomocných látek
- Benzalkonium-chlorid
- Dihydrogenfosforečnan draselný
- Hydrogenfosforečnan draselný
- voda na injekci
- čirý bezbarvý roztok
Terapeutické indikace
- Ošetření a léčení při stavech s vysycháním rohovky a spojivek
- Při poruchách tvorby slz
- Při nedovírání očních víček
- K dodatečnému zvlhčování při nošení tvrdých kontaktních čoček.
Dávkování a způsob podání
- 1 gtt až 6xd do spojivkového vaku
- Většinou bývá nutné používat umělé slzy doživotně
- Výjimku tvoří sekundární přechodné poruchy
- Bez omezení věku pro dospělé i děti
Kontraindikace
- Hypersenzitivita na léčivé látky / pomocnou
Zvláštní upozornění a opatření
- Benzalkonium-chlorid může způsobit dráždění očí
- Obarvuje měkké kontaktní čočky
- Nesmějí přijít do kontaktu s přípravkem Siccaprotect
- Nesmějí nosit měkké kontaktní čočky
- Tvrdé kontaktní čočky musí před aplikací odstranit a počkat min. 15 minut před vrácením do oka
- Interakce Nejsou popsány
- Nebyly nalezeny nepříznivé účinky calcium-pantothenátu na fertilitu ani na vývoj plodu
- 20 minut po vkápnutí do oka může přetrvávat mírně rozmazané vidění.
Nežádoucí účinky
- Vzácně hypersenzitivní reakces pocity mírného pálení ve spojivkovém vaku.
- S výrazně porušenou rohovkou u očních kapek s fosfáty vzácně hlášeny případy kalcifikace rohovky
Předávkoání
- Akutní toxicita dexpanthenolu
- V pokusech na zvířatech pohybuje v rozsahu gramových dávek na 1 kg tělesné hmotnosti.
Farmakodynamické vlastnosti
- Při poškození epitelu i hlubších vrstev
- Vzniká lokální nedostatek koenzymu A
- Dexpanthenolum (panthenolum)
- Prekurzor kyseliny pantothenové (vitaminu B5)
- Je složkou koenzymu A
- Acetylkoenzym A pak zasahuje do metabolismu lipidů, sacharidů i aminokyselin
- Ve zvýšených koncentracích ve tkáních s intenzivním metabolismem - např. v kůži
- Dexpanthenol dobře proniká do hloubky
- Podporuje granulační proces
- Působí antiflogisticky
- Antipruriginózně
- Urychluje hojení neinfekčních zánětů oka
- Polyvinylalkohol
- Zvyšuje viskozitu a lpění na rohovce
- Prodlužuje jeho působení
- Pomocné látky:
- Benzalkonium-chlorid
- Působí na grampozitivbní i gramnegativní mikroby
- Některé druhy pseudomonád jsou rezistentní
- Fosfáty v roztoku
- Regulují osmolaritu a pH
Farmakokinetické vlastnosti
- 0,05 ml roztoku několikrát denně do spojivkového vaku neumožňuje detailnější sledování farmakokinetiky v celém organismu
- Dexpanthenol je látka po mnoho let klinicky používaná
- Seznam pomocných látek
- Benzalkonium-chlorid
- Dihydrogenfosforečnan draselný
- Hydrogenfosforečnan draselný
- voda na injekci
Další
- Inkompatibility
- S měkkými kontaktními čočkami
- Doba použitelnosti- 3 roky.
- Po prvním otevření: 4 týdny.
- Uchovávejte při teplotě do 25 °C.
- DRŽITEL ROZHODNUTÍ O REGISTRACI
- URSAPHARM spol. s r.o.
- Datum první registrace: 18.10.2000
- DATUM REVIZE TEXTU 1.7.2016
