Farmakologické parametry

Podání

• Can be taken intravenously
• By mouth
• Inhaled as a mist
• Dietary supplement [1]

Oral acetylcysteine

• Identical in bioavailability to cysteine precursors
• Solution is usually mixed with another liquid
• Such as cola to decrease nausea and vomiting [2]
• Drink the medication within 1 hour of mixing
• Tell your doctor if you vomit within 1 hour after taking it [2]

I.v.

• 3% to 6% of people severe, anaphylaxis-like allergic reaction
• May include extreme breathing difficulty (due to bronchospasm)
• Decrease in blood pressure
• Rash
• Angioedema
• Nausea and vomiting [1]
• Repeated doses i.v. acetylcysteine
• Allergic reactions to progressively worsen [1]

Overdosage

• Large doses causing nausea
• Oral overdosage could result in side effects such as nausea, vomiting and other gastrointestinal symptoms [4]
• Nausea can occur for a few minutes within an hour of taking two or three 600 mg pills on an empty stomach.
• Appears to be a safe nutrient as long as the dosage is kept to less than 500 mg
• Has anticoagulant and platelet-inhibiting properties [4]
• Rare side effects could include bronchospasm
• More likely when used by the intravenous route [4]