MUDr. Dana Maňasková


Vyhledávání na medicinman.cz
 

Dávky jódu

Adequate Intake (AI)

European Food Safety Authority, 2014

  • Iodine is essential for the synthesis of thyroid hormones.
  • Based on a large epidemiological study in European school-aged children
    • Showing that goitre prevalence is lowest for a urinary iodine concentration above around 100 mcg/L
    • Urinary iodine concentration of over 100 mcg/L
      • Accepted as the threshold indicating sufficient iodine intake of school-aged children [1]
  • In the absence of similar suitable data for other age groups
    • Proposed that this threshold also be applied for adults, infants and young children
    • Taking into account urinary volume and an absorption efficiency for iodine of 92 % [1]
Takže z málo dat dali dohromady hypotézu, že když každý dospělý bude mít alespoň 150 mcg/d iodu, tak ve většině případů snad nebude mít strumu = to je interpretace pro následující čísla = opravdové denní minimum pro zachování zdraví většiny lidí

  • Adults 150 mcg/day
  • Infants aged 7–11 months and for children 70 mcg/day - 130 mcg/day
  • Pregnant women 200 mcg/day
    • Additional needs due to increased maternal thyroid hormone production
    • Iodine uptake by the fetus, placenta and amniotic fluid [1]
  • Lactating women 200 mcg/day
    • Large iodine stores in conditions of adequate iodine status before pregnancy
    • Considers that a full compensation for the iodine secreted in breast milk is not justified for the derivation of an AI [1]

Iodine Intake to Reduce Covid-19 Transmission and Mortality

  • A preliminary technical report here showed evidence that increasing our iodine intake within safe levels
    • Might be sufficient to help against covid.
  • This report adds subsequently identified information that conclusively shows that raising our iodine intake within safe levels will fully supply the body with amounts that it needs to fight covid in three ways:
    • On the skin before you touch your face
    • In your nasal passages before you are infected
    • If infected, by helping kill infected cells that are replicating the virus
  • The evidence is replete in the literature, including reasons why the information is not public via the government or mainstream media.
    • This paper summarizes this all and suggests grassroots action.
  • Iodine is known to deactivate coronavirus very quickly at very low concentrations.
  • Multiple published scientific analyses confirm that
  • Best fight any coronavirus, our iodine intake needs to attain the safe upper limit specified by the United Nations Food and Agricultural Organization. (FAO)
  • That amount is much more than the FDA’s Recommended Daily Allowance (RDA), which is the amount we currently average.
  • The FAO dose is
    • Weight dependent at 30 micrograms of iodine per kiligram of body mass – 13mcg/lb.
    • For a 60kg (176 lb) person the amount is 2400 micrograms = 2,4 mg
  • Some pacific rim countries already use oral iodine against covid.
  • Three countries there are starting tests with an iodine nasal treatment against covid
    • To give medical workers extra protection.
  • Iodine being one of the World Health Organization’s listed essential medicines and the CDC’s reference list of covid disinfectants
    • Raise our daily iodine intake to the FAO safe upper limit (30mcg/kg)
      • Most of us will have no negative side effects.
  • Using Lugol’s Solution (a formulation not a particular brand)
    • Specific form of iodine on the World Health Organization's List of Essential Medicines
    • Help reduce the need for social distancing and to reopen the economy, spread the word
  • (1) Known to deactivate coronavirus,
  • (2) Known role in relevant immune functions inside the body
  • (3) Known to be safe for people to take
  • (4) Broad availability at low cost
  • (5) No additional FDA approval required.
  • (6) And a lack of contrary evidence.
    • Iodine was the only item found that met all of the criteria
  • Iodine use has two parts
    • Intake for use inside the body
    • External for touch surfaces, skin, etc.
  • Multiple published scientific analyses confirm that, to best fight any coronavirus, our iodine intake needs to attain the safe upper limit
    • Specified by the United Nations Food and Agricultural Organization (FAO).
  • That amount is much more than the FDA’s Recommended Daily Allowance (RDA)
    • Which is the amount we currently average
    • United States iodine RDA for adults is 150 mcg and its UL is 1100 mcg
  • FAO, 2001 makes clear that the 150 mcg RDA only regards iodine requirements for thyroid function
    • That same document specifies a safe upper limit for iodine intake as 30mcg/kg of weight which is higher than the United States UL for adults heavier than 80-pounds
  • 1. Deactivation of covid in the nose
    • By the presence of enough iodine in the nasal mucus.
  • 2. Iodine in sweat to deactivate covid on skin
    • Before it can enter the body.
  • 3. Participation in apoptosis to kill cells infected
    • With covid to stop the cells replicating the covid virus
  • The above list of functions is not the full set of addition roles for iodine in the body
    • Technical details regarding the full range of body’s uses of iodine are available at (Aceves, et al., 2013) and (Rychlik, 2017)
  • Less technical summaries of some of those uses iodine are available at (Derry, 2009) and (Rondon, 2019)
  • Reference (Aceves, et al., 2013) directly estimates that the
    • Total iodine required to support all functions is least 3 mg/day for certain pathologies
  • Another reference (Rychlik, 2017) that examines the iodine requirements to support all functions recommends
    • “In order to maintain optimum health, adults need 2-5 mg of iodide daily.”
    • Their recommendation is in line with “upper safe limit of dietary intake of iodine established by FAO (30 mcg/kg/day)
  • 1. Iodine requirements for nasal mucus are
    • Estimated in a publication this month (Kirk-Bayley, et al., 2020)
      • Proposes nasal spray to deactivate covid on inhalation
    • Their estimate is 330 mcg sprayed into the nasal passages every 6 hours (4 times per day)
    • That. equates to total of 1320 mcg per day for the nasal passages.
    • The body will exhale some of
  • 2. Iodine requirements for sweat
    • Are available in another study (MAO, et al.).
    • Measured iodine loss in sweat at 37 mcg/liter of sweat
    • It is a substantial amount compared to the RDA of 150 mcg, especially during covid induced fever
  • 3. Iodine intake requirements for apoptosis
    • Could not be found in the literature
    • Requirement may be more about available iodine stores than daily intake
    • (Aceves, et al., 2013) showed that apoptosis rates are limited by iodine levels
      • Augmenting with 5000 mcg/day of I2 per day for several weeks
        • Did significantly increase apoptosis rates
    • For fighting covid, 150 mcg is insufficient
    • Very strong correlation between low iodine and cancer is shown in (Kargar, et al., 2017) and similarly in (Rondon, 2019)
    • Traditional Japanese iodine intake has been 1000 to 3000 mcg
      • They are among the longest lived as a group in the world
      • With much lower cancer rates than in the United States. (Zava, et al., 2011)
    • FDA UL of 1100 mcg is not sufficient, but it is better than the RDA of 150mcg
Fischer at. all 2011 prokázali, že aby se do plicních sekretů dostalo dost iodu, tak je potřeba, aby se jeho hladiny v krvi zvýšily z nanomolární koncentrace na mikromolární a účinnou p.o. dávku prokázali jako 130 mg - která vedla k dostatené virucidní koncetraci jódu v sekretech dýchacích cest. Ale na rozdíl od autora této studie nedoporučuje dodržovat denní příjem zvýšený. Mne připadá strategie s pohotovstním podáním vyšší dávky jodu v případě infekce a akutní potřeby lepší - pravděpodobně bezpečnější než jeho trvale vyšší užívání. Nicméně údaje o příjmu jódu ve vztahu k nádorům aj. jsou velmi zajímavé.



Doporučený denní příjem jódu

Česká republika

  • Vyhláška č. 450/2004 Sb., o označování výživové hodnoty potravin
    • 150 mcg/den
  • Obecně se doporučuje
    • 150-200 mcg/den
  • Příjem pod 50 mcg/den
    • Není štítná žláza schopna udržet přiměřenou hormonální sekreci
      • Zvětšuje se a vzniká struma
      • Někdy i hypotyreóza (Límanová a kol., 1995)

ICCIDD (Mezinárodní komise pro řešení chorob z nedostatku jódu)

  • 90 mcg/den pro předškolní děti (0-59 měsíců)
  • 120 mcg/den pro školní děti (6-12 let)
  • 150 mcg/den pro dospělé (nad 12 let)
  • 200 mcg/den pro těhotné a kojící ženy

Těhotné

  • Doporučený denní příjem jódu:
    • 130 ug/d Evropa
    • 175 ug/d USA [4]
    • 200 ug/d WHO,ICCIDD
    • 200-250 mcg/den ČR (vyhláška č. 450/2004 Sb.)

Kojící

  • Doporučený denní příjem jódu:
    • 130 ug/d Evropa
    • 200 ug/d WHO, USA, ICCIDD [4]
    • 200-250 mcg/den ČR (vyhláška č. 450/2004 Sb.)
O úroveň výše

Poslední aktualizace: 27. 11. 2020 16:18:38