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A Comparison of the Effectiveness of Tincture of Iodine and potassium Iodide on Chronic Sinusitis Patients with Biofilm.

• Several factors may influence the results of bacteriological and fungal studies in chronic rhinosinusitus (CRS) patients.
• Antibiotics perform poorly against bacteria and fungi in biofilm
• Potential utility of tincture of iodine and potassium iodide on bacterial and fungal elements within the biofilm in chronic rhinosinusitus patients.
• Bacteriology was studied in 12 consecutive adult patients presenting with CRS who underwent functional endoscopic sinus surgery.
• Ethnocide tissue from all patients was treated with the same concentrations of tincture of iodine or potassium iodide at different time intervals.
• The ethnocide tissues were examined for live/dead bacterial and fungal cells by Baclight assay.
• Tincture of iodine and potassium iodide were able to kill bacterial and fungal cells in ethnocide tissue.
• We performed quantitative analysis and showed that tincture of iodine is slightly more effective than potassium iodide.
• The tincture of iodine treatment on the ethnocide tissues yielded a higher percentage of dead bacterial or fungal cells compared to potassium iodide treatment with similar concentrations.
• www.researchgate.net/publication/331706994_A_Comparison_of_the_Effectiveness_of_Tincture_of_Iodine_and_potassium_Iodide_on_Chronic_Sinusitis_Patients_with_Biofilm