Kontraindikace podání jodidu draselného

Who should not take potassium iodide (KI) or should have restricted use?

Extremely rare conditions associated with an increased risk of iodine hypersensitivity

Hypersensitivity to the active substance, to iodine or to any of the excipients listed in section
Renal failure
Hypocomplementaemic vasculitis
Dermatitis herpetiformis
[ www.medicines.org.uk/emc/medicine/5234#gref ]

Patients with thyrotoxicosis treated medically, or patients with a past history of thyrotoxicosis treated medically who are now off treatment and apparently in remission, may be at risk.
Iodine induced hyperthyroidism

May be precipitated in patients with asymptomatic nodular goitre or latent Graves` disease, who are not under medical care.

Potassium salts should be given cautiously to patients with renal or adrenal insufficiency, acute dehydration or heat cramp.
Care should be exercised if potassium salts are given concomitantly with potassium-sparing diuretics, as hyperkalaemia may result

Unless doses to the thyroid from inhalation rise to levels threatening thyroid function

Neonates in the first days of life are at particular risk from exposure to radioactive iodine and blocking of thyroid function by overload of potassium iodate. The fraction of radioactive uptake is fourfold greater than all other age groups.
The neonatal thyroid is especially sensitive to functional blocking caused by overload of potassium iodate.
Transient hypothyroidism during this early period of brain development can result in loss of intellectual capacity.
If stable iodine is given to neonates close follow up of thyroid function is essential.
For neonates who have been administered potassium iodate in the first few weeks of life TSH levels and, if necessary, T4 levels should be monitored and appropriate replacement therapy given.

Potassium iodide can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
www.everydayhealth.com/drugs/potassium-iodide

Congenital goitre and hypothyroidism have been reported when iodides are administered to pregnant women.

Prophylactic administration of iodate to the pregnant mother should be effective for the foetus also.
Throughout pregnancy the number of doses of potassium iodate should be kept to a minimum and repeat doses should be avoided
In areas of iodine deficiency prolonged dosage could lead to maternal or foetal thyroid blockage with possible consequences for foetal development.
If potassium iodate is administered late in pregnancy, the thyroid function of the new-born should be monitored.
This is generally met by routine screening in the neonatal period.
For neonates who have been administered potassium iodate in the first few weeks of life TSH levels and, if necessary, T4 levels should be monitored and appropriate replacement therapy given.
Pregnant women with active hyperthyroidism must not take potassium iodate because of the risk of foetal thyroid blockage.
Iodine is actively transported into breast milk, however those breast feeding should continue to do so