Laktát
Tvorba
- Ve svalovině
- Erytrocyty
Zvýšené hladiny
- Strenuous exercise
- Heart failure
- Severe infection (sepsis)
- Shock s hypoxií tkání
- Liver is severely damaged or diseased
- Liver normally breaks down lactic acid
- Severe lung disease or respiratory failure
- Pulmonary edema
- Severe anemia
- Accumulates in the body if glucose cannot be completely broken down due to lack of oxygen or insulin
- Uncontrolled diabetes
- Leukemia
- AIDS
- Glycogen storage diseases
- Glucose-6-phosphatase deficiency
- Drugs and toxins
- Salicylates
- Cyanide
- Methanol
- Metformin
- Inherited metabolic and mitochondrial diseases
- Muscular dystrophy
- Affect normal ATP production
Lactic acidosis
- život ohrožující stav
- Riziko vzniku
- Terapie metforminem a sulfonylureou when heart or kidney failure or a severe infection is also present
- Symptomy
- Rapid breathing
- Excessive sweating
- Cool and clammy skin
- Sweet-smelling breath
- Belly pain, nausea or vomiting
- Confusion, and coma
