nemoci-sympt/GASTROENTEROLOGIE/mikrobiom/actinobacteria-Proteobacteria

The Actinobacteria/Proteobacteria ratio

• Is another measure of the relative abundance of two major phyla of bacteria in the gut microbiome.
• Actinobacteria and Proteobacteria are also dominant phyla in the human gut
• Changes in their relative abundance have been associated with various diseases and conditions.

Decreased ratio of Actinobacteria to Proteobacteria

• May be associated with various gastrointestinal disorders
• Inflammatory bowel disease
• Colorectal cancer
• Patients with inflammatory bowel disease
• Had a significantly lower ratio of Actinobacteria to Proteobacteria compared to healthy individuals
• Changes in this ratio may be linked to other conditions
• Obesity, type 2 diabetes, and cardiovascular disease.
• Actinobacteria/Proteobacteria ratio is just one measure of the gut microbiome
• Clinical relevance is still being explored.
• Firmicutes/Bacteroidetes ratio