nemoci-sympt/GYNEKOLOGIE/estrogenni-deficience
Hypoestrogenism přičiny
- Commonly found in women who are postmenopausal
- Premature ovarian failure
- Suffering from amenorrhea
- Associated with hyperprolactinemia [1]
- Use of gonadotropin-releasing hormone (GnRH) analogues
- Treatment of endometriosis [1]
- Linked to scoliosis and young women with type 1 diabetes mellitus [1]
Hypogonadotropic hypogonadism
- Due to hyperandrogenism
- Lactation
- Certain medications
- Androgens/anabolic steroids
- Progestogens
- Prolactin releasers
- GnRH analogues
- Pituitary gland/hypothalamus damage
- Isolated hypogonadotropic hypogonadism
- Kallmann syndrome
- CHARGE syndrome
- GnRH insensitivity
Hypergonadotropic hypogonadism
- Due to menopause
- Premature ovarian failure
- Certain medications
- Aromatase inhibitors
- CYP17A1 inhibitors
- Gonadotropin insensitivity
- Inborn errors of steroid metabolism
- Aromatase deficiency
- 17?-hydroxylase deficiency
- 17,20-lyase deficiency
- 3ß-hydroxysteroid dehydrogenase deficiency
- cholesterol side-chain cleavage enzyme
- Steroidogenic acute regulatory protein deficiency
Symptomy
- Hot flashes
- Headaches
- Lowered libido
- Breast atrophy
- Reduced bone density
- Secondary osteoporosis
- Atrophic changes
- PH change in the vagina
- Dyspareunia
- Limited genital arousal
- Changes in the four layers of the vaginal wall
- One of the major risk factors for developing uncomplicated urinary tract infections (UTIs)
- In postmenopausal women who do not take hormone replacement therapy [1]
