leky-latky/aDIPOQ-gen/funkce-adiponektinu

Funkce úvod

• Protein secreted by adipose tissue
• Reduce insulin resistance
• Reuce atherogenic damage
• Actions in other tissues
• Influences gonadotropin release
• Normal pregnancy
• Assisted reproduction outcomes
• Major link between obesity and reproduction
• Higher levels of adiponectin are associated with
• Improved menstrual function
• Better outcomes in assisted reproductive cycles
• Appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties
• Inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein
• Attenuates inflammatory responses
• Modulating signaling pathways in a variety of cell types
• Important factor in chronic liver diseases and chronic kidney diseases
• Some cancer cell types express adiponectin receptors
• May act on tumour cells directly [2]