leky-latky/cytokiny/20-chemicky-popis
Adenines and adenosines with N6-substitution
- May be released into the cytosol
- Subsequently into body fluids
- Result of tRNA turnover
- IPR was detected in human urine (Chheda and Mittelman 1972) [1]
Adenin derivatives at N6-position -plant cytokinins
- Isoprenoid
- Aromatic side chain
- Synthetic compounds with cytokinin activity
- Can have other scaffolds
- Phenylureas - best known example [1]
- In certain tRNA species of all organisms with the exception of Archea
- In mammals, an N6-isopentenyladenosine (iPR) moiety forms part of tRNA[Ser]Sec
- Facilitates codon-anticodon interactions
- Contributes to the efficiency of selenoprotein synthesis
Isoprenoid and aromatic cytokinins occur as
- Free bases,
- Ribosides,
- Ribotides,
- N-glucosides
- Amino acid conjugates
Isoprenoid cytokinins
- Cis- and trans-zeatin (tZ)
- And their analogues
- With a saturated side chain
- Dihydrozeatin
- With hydroxylated isoprenoid side chains
- O-glycosides
- Without an hydroxyl group
- N6-isopentenyladenine, iP
- Present in all plants
- N6-furfuryl side chain
- Kinetin (K)
- First identified cytokinin [1]
Aromatic cytokinins
- With N6-benzyl substituents
- Only in certain taxa (Horgan et al. 1975; Strnad 1997) [1]
