leky-latky/enzymy/proteazy-virove

Viral proteases

• Functional involvement in the processing of proteins of viruses that cause certain fatal diseases such as AIDS and cancer
• Serine, aspartic, and cysteine peptidases
• Found in various viruses [11]
• Virus-encoded peptidases are endopeptidases
• no metallopeptidases [11]
• Retroviral aspartyl proteases
• Required for viral assembly and replication
• Homodimers
• Expressed as a part of the polyprotein precursor
• Mature protease is released by autolysis of the precursor [11]
• Extensive research has focused on their interaction with synthetic inhibitors [11]