leky-latky/glutaminaza/funkce-vyznam

Funkce

• Glutaminase catalyzes the stoichiometric conversion of L-glutamine to L-glutamate and ammonium ions
• First step of glutaminolysis [1]

Nádory obecně

• Metabolic reprogramming, many cancer cells become glutamine addicted
• Depend on a high consumption of glutamine for their survival and proliferation [1]