leky-latky/glutaminaza/snizena-aktivita

Caytaxin

• Regulates the intracellular localization and activity of KGA
• Relocalized KGA from cell body to neurite terminals
• And reduced glutamate levels by inhibiting its activity (Buschdorf et al., 2006). [1]

Kyselina glutamová - glutamát

• (GLS) strongly inhibited by the product glutamic acid
• Glutamate
• Caused inhibition of glutaminase by reversing tetramesiation
• Z tetramerů se staly opět inaktivní dimery (Godfrey et al., 1977; Morehouse and Curthoys, 1981) [1]