Uvolnění - výlev histamínu

Polymyxin

• Found to stimulate histamine release.

Basophil sensitized by IgE antibodies exposed to the appropriate antigen

• IgE attached to their membranes
• histamine release immunologic

Allergens bind to mast-cell-bound IgE antibodies

Curare alkaloids

• Displace histamine in granules
• Cause its release

Morphine

• Displace histamine in granules
• Cause its release