MUDr. Dana Maňasková


Vyhledávání na medicinman.cz
 

leky-latky/jod/transport-jodu

NIS

  • Non-regulated iodide accumulation, without organification
  • In the lactating mammary gland
  • Salivary
  • Parotid glands
  • Gastric mucosa
  • Small intestine
  • Choroid plexus
  • Ciliary body of the eye
  • NIS is expressed in other tissues
  • In the lung, where oxidation of iodide improves anti-viral defenses
  • Endogenous NIS expression occurs in breast cancer and cholangiocarcinoma
    • Exploring the use of 131I- to treat these types of cancers
  • NIS transports perrhenate defines 188ReO4-
    • A candidate to increase radiation dose delivery to these tumors
  • Transduction of viral vectors containing the cDNA of NIS under the control of heterologous promoters
O úroveň výše

Poslední aktualizace: 12. 12. 2023 1:21:39