leky-latky/q10/deficit
- CoQ deficiency induces an early autophagy response, as it is suggested in the brain of Coq9R239X at 2 months of age, and as it has been reported in vitro
www.thelancet.com/article/S2352-3964(19)30165-3/fulltext
Deficit koenzymiu Q
- Five major phenotypes: encephalomyopathy, severe infantile multisystemic disease, nephropathy, cerebellar ataxia, and isolated myopathy
www.thelancet.com/article/S2352-3964(19)30165-3/fulltext
- CoQ deficiency induces oxidative stress in vitro and in vivo and the pons and diencephalon of Coq9R239X mice show increased signals of markers of oxidative damage
