nemoci-sympt/BAKTERIALNI-INFEKCE/chlamydie/symptomy-a-asociovana-onemocneni/neuropatie

Peripheral Nerve Inflammation and Central Pain:

Reflex Sympathetic Dystrophy

Symptomy

• Deep, grinding bone pain
• Crushing quality
• Does not correspond to any recognised area supplied by a sensory nerve
• Can travel along a limb
• Shoulder, next in the fingers etc.
• Can suddenly go, suddenly return [47]
• More severe form
• Accompanied by a redness of the limb
• Dilation of the superficial veins
• Increase in sweating in the limb
• Use of the limb may be limited
• Often an exaggerated perception of skin stimuli
• Light breeze may be felt as painful - seems transient :47::
• Painful tics
• Muscle fasciculations may also occur [47]

• Common in those with a chronic Chlamydia pneumoniae infection
• Many people develop it during bacterial killing
• Severity seems to depend on bacterial load and placement
• Usually mild
• Often does not last long
• Limb can remain red or mottled for some months
• Complete resolution is the rule [47]

• Severe thalamic pain of central origin can also occur in MS
• Usually long-lasting
• As described above
• Related to a bacteria-killing agent
• When metronidazole, for instance, is added to protein-synthesis inhibitors [47]

Etiologie

• Asi něco jako Sudeckův syndrom, jen ne v kloubu a po zjevném úrazu, ale jen tak
• Vznik/zhoršení po ATB terapii, následné vymizení
• Typical of damage to a large peripheral nerve
• Caused by injuries - often quite minor - to a nerve
• May occur after a virus infection [47]

• Chronic Chlamydia pneumoniae infection
• By acute inflammation associated with the destruction of a local bacterial collection (?) [47]

• Mechanism of the pain is not fully understood
• V.s. involve stimulation of the thalamus
• Pain is thus generated in the brain [47]