Historie

Historie

• 1898 objeveny - Nocard and Roux
• First isolate a mycoplasma species in culture from bovine pleuropneumonia [5]
• 1937 Dienes and Edsall - isolated the first pathogenic human mycoplasma, M. hominis, from a Bartholin's gland abscess
• 1943 - Peterson - cold agglutinin
• High titers of cold agglutinins in patients with primary atypical pneumonia [6]
• 1944 - Eaton's agent
• Isolated another Mycoplasma from a patient with atypical pneumonia [5]
• Could be grown in chicken embryos and passed through a filter that excluded normal bacteria
• Agent did not grow on the standard pleuropneumonia-like organism (PPLO) media of the time [5]
• 1962 named M. pneumoniae by Chanock et al [7]
• 1963 determined that Eaton’s agent was a bacterium [5]