Kawasakiova nemoc

Larazotide acetate

Study on Kawasaki disease mice

• Condition very similar to MIS-C
• Mice with elevated zonulin levels
• Could be successfully treated with larazotide acetate

• 2000, Fasano and his team at the University of Maryland School of Medicine
• Discovered zonulin
• Regulates intestinal permeability by opening the tight junctions between gut epithelial cells in the small intestine.
• Passage of substances from the gut lumen into the bloodstream, including gluten
• Larazotide acetate zpevňuje TJ, byl testován u celiakie
• www.sciencedaily.com/releases/2021/05/210525160845.htm