Možnosti na JIP a ovlivnění lymfedému

Continuous Blood Purification - CBP - role in the treatment CLS [17]

• Can enhance
• Clearance of inflammatory mediators
• Improve pulmonary gas exchange
• Keep hemodynamics stable control of azotemia
• Reduce fluid overloading
• Entering macromolecular synthetic colloids
• Be convenient for nutrition support
• Improve oxygen metabolism or tissue perfusion in patients
• Control SIRS symptoms
• Prevent the development of the disease to the MOD
• Improve the survival rate in critically ill patients
• Can make rapid absorption and removal of endotoxin in blood
• Correct acidosis
• Improve the body’s homeostasis
• Protective effect on vascular endothelial function
• Can improve coagulation dysfunction in vivo because of heparin
• Can reduce blood coagulation cascade [17]

Endothelial glycocalyx

• Layer of glycoproteins secreted by the endothelium
• Larger macromolecules present in plasma are most restricted in passage owing to their large size and negative charge
• Proteins initially present in plasma, from albumin to complement and immunoglobulins
• Found within interstitial ?uid at lower concentrations than in plasma because of this ?ltration barrier [51]