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Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies

May not always be associated with therapy-related myeloid neoplasms
Deletion 7q is a common chromosomal abnormality in myeloid neoplasms
Detection of del(7q) in patients following cytotoxic therapies is highly suggestive of an emerging therapy-related myeloid neoplasm.
In this study, we describe 39 patients who acquired del(7q) as a sole abnormality in their bone marrow following cytotoxic therapies for malignant neoplasms.
www.nature.com/articles/modpathol201667