nemoci-sympt/METABOLISMUS/downuv-syndrom

Časná intervence nezbytná - období nejsilnější neurogeneze je prenatálně/novorozenci

Zvýšená neurogeneze trvá v nějakém rozsahu cca do 7 let, kdy je mozek schopen dohnat lecos !!!
The exciting discovery that trisomy-linked brain abnormalities can be prevented with early interventions gives us reason to believe that treatments during pregnancy may rescue brain development in fetuses with DS.
Intellectual disability (ID) is the most serious problem of Down syndrome (DS)

Scientists worldwide are currently trying to discover interventions that improve or even rescue ID in DS

Therapy for DS may be possible
Appropriately timed therapies may have a large impact on ID
This achievement would give children with DS the opportunity of a normal and autonomous life

"Since brain alterations in Down syndrome start to be present prenatally, the prenatal period represents an optimum window of opportunity for therapeutic interventions," researchers in Italy and France wrote in a study on the importance of timing for drug treatment of the condition. "Importantly, recent studies clearly show that treatment during the prenatal period can rescue overall brain development and behavior and that this effect outlasts treatment cessation.
www.upi.com/Health_News/2021/06/26/coronavirus-children-weight-diabetes-study/6551624655056/

Timing of therapies for Down syndrome: the sooner, the better
DOI: 10.3389/fnbeh.2015.00265
=www.researchgate.net/publication/282904585_Timing_of_therapies_for_Down_syndrome_the_sooner_the_better==

Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice

Among the triplicated genes DYRK1A, SIM2, DSCAM, GIRK2, Olig1, and Olig2, SYNJ1, and APP

Various therapies have been attempted during the past few years in the Ts65Dn mouse model

Showing that it is possible to pharmacologically improve cognitive performance and different aspects of the DS brain phenotype

"There is no evidence that any nutritional supplement enhances the prognosis. This tactic tends to prey mostly on the parents of infants and young children with Down syndrome, who are most vulnerable to the suggestion that they might be bad or neglectful parents if they don’t give their children these products." [October 18, 1998]

Možnost nějaké kompenzace zcela jistě někde v těch metabolických drahách existuje
Ale asi člověk snadno naletí na něco, co nebude mít žádný vzýnam
Zatím na to nebude moc studií, ale určitě se už dá dnes něco rozumného podávat, aby to alespoň nějaký efekt mělo