nemoci-sympt/METABOLISMUS/marfanuv-syndrom/prognoza
- Průměrný věk života pacientů s Marf. syndr.
- 35 - 40 let [1]
- The leading cause of premature death in MFS patients is
- Progressive dilation of the aortic root and ascending aorta [9]
- Causing aortic incompetence and dissection [9]
- Reduced fibrillin deposition
- By a dominant-negative effect of abnormal fibrillin molecules
- Nespecifický pro Marf. syndr.
- Ale prognostic and possibly diagnostic significance [14]
Literatura:
[1] www.marfanuvsyndrom.websnadno.cz/marfanuv-syndrom.html
[9] FBN1 Gene - GeneCards | Protein | Antibody [Internet]. [citován 2012 říj 14]. Available z: www.genecards.org/cgi-bin/carddisp.pl?gene=FBN1
[14] OMIM Entry - # 154700 - MARFAN SYNDROME; MFS [Internet]. [citován 2012 říj 14]. Available z: omim.org/entry/154700
