nemoci-sympt/METABOLISMUS/mitochondrie/metabolizmus/krebsuv-cyklus/eakce-krebsova-cyklu/citrat
Citrát
- Present to some extent in all plant and animal tissues
- First isolated by the German biochemist, Karl Wilhelm Steele in 1784
- citric acid relieve from
- Fatigue
- Poor digestion
- Cold and flu infections
- Asthma
- Hypertension
- cholesterol [9]
- Control by citrate would be expected to be absent in rapidly dividing tumors which characteristically have low mitochondrial levels of citrate [13]
- Může být transportován z Krebosva cklu z MTCH do cytosolu, kde přeměny:
- ATP citrate lyase
- Z CoA, ATP, ADP+P1 vznik Acetyl-CoA
- Oxalacetate
- Malate dehydrogenase
- Z NADH vznikne NAD+
- Malate
- Malic enzyme
- Z NADP+ vznikne NADPH, a CO2
- Pyruvát
- Zpět transportován do MTCH
Citrát v cytosolu buňky
- Blokuje glykolýzu
- Slouží k syntéze MK
Citrát
- Present to some extent in all plant and animal tissues
- First isolated by the German biochemist, Karl Wilhelm Steele in 1784
- citric acid relieve from
- Fatigue
- Poor digestion
- Cold and flu infections
- Asthma
- Hypertension
- cholesterol [9]
- Control by citrate would be expected to be absent in rapidly dividing tumors which characteristically have low mitochondrial levels of citrate [13]
- Může být transportován z Krebosva cklu z MTCH do cytosolu, kde přeměny:
- ATP citrate lyase
- Z CoA, ATP, ADP+P1 vznik Acetyl-CoA
- Oxalacetate
- Malate dehydrogenase
- Z NADH vznikne NAD+
- Malate
- Malic enzyme
- Z NADP+ vznikne NADPH, a CO2
- Pyruvát
- Zpět transportován do MTCH
Citrát v cytosolu buňky
- Blokuje glykolýzu
- Slouží k syntéze MK
