nemoci-sympt/METABOLISMUS/wilsonova-choroba/symptomy
Neurologic deterioration with treatment
- Recognize that some patients may develop worsening neurologic symptoms when therapy is initiated
- Chelating agent needs to be stopped and the patient should be run on zinc acetate alone
- Patients on long-term treatment who show signs of progressive neurologic symptoms on chelating agents
- Medication compliance and dietary compliance require review
- + assessment of the efficacy of laboratory testing [1]