nemoci-sympt/OCNI/astigmatismus-keratokonus/protektivni-terapie

Topical Retinoids

• Gold standard for clinically effective topical antiaging products
• Vitamin A, its derivatives
• All-trans retinoic acid (RA)
• Retinaldehyde, retinol, and various retinyl esters
• Retinoic acid receptors (RARs) and retinoid X receptors (RXRs)
• Increasing the amount of type I procollagens
• Decreasing the amount of MMPs
• RA
• Increases the amount of type I, III, and VII collagens in the dermis
• Can reorganize the dermal collagen into new woven bundles
• RA stimulates normalization of the elastic tissue organization and GAG deposition in the dermis
• In clinical trials, topical retinoids are
• Clinically effective for the treatment of dermal aging, including
• Wrinkles, roughness, and laxity
• Can be irritating to a significant percentage of the population
• Retinol, which metabolizes to retinaldehyde and retinoic acid,
• Found to be less irritating than retinoic acid
• Widely used as an ingredient for antiaging cosmeceuticals
• www.mdpi.com/1422-0067/20/9/2126

• PS: když to funguje na kůži a podkoží, co by to nemělo fungovat na rohovku.