Nádory děložního hrdla
Active molecule of U. dioica is a rare lectin (carbohydrate-binding protein), U. dioica agglutinine (UDA, accession number P11218 in Protein Data Bank) [106], isolated from the U. dioica aqueous roots extract (Wagner et al. 1994) [85]. This molecule demonstrated in vitro anti-proliferative properties on human cervical cancer HeLa cells and human epidermoid carcinoma A431 cancer cells. On HeLa and A431 cells UDA inhibited the binding of EGF to its receptor with an IC50 of 5 and 21 µg/mL, respectively, after 24 h exposure [107].
Https://www.mdpi.com/1420-3049/24/15/2753