Klinické studie - neví se

Belotecan

• Camptothecin analogue

Phase II trials

Phase III trial comparing EP with cisplatin/belotecan in patients with previously untreated ES-SCLC is running in Asia

• erj.ersjournals.com/content/35/1/202

Ipilimumab-nivolumab

• In pre-frontline immunotherapy stratus had some data for efficacy
• www.onclive.com/view/treatment-options-for-relapsed-small-cell-lung-cancer

Jared Weiss, MD: Less than that: once or less than once a year.

Obatoclax

• A Bcl-2 inhibitor

Phase I/II trials including patients with SCLC

• erj.ersjournals.com/content/35/1/202

Bevacizumab

• A monoclonal antibody that binds vascular endothelial growth factor (VEGF)
• Treatment of advanced-stage NSCLC
• Evaluated in SCLC
• Two cooperative group phase II trials evaluating the use of bevacizumab in the treatment of ES-SCLC are pending
• erj.ersjournals.com/content/35/1/202

Studie v Evropě

• clinicaltrials.gov/search?cond=Small%20Cell%20Lung%20Carcinoma&locStr=Europe&distance=50&aggFilters=ages:adult%20older,sex:m,status:not%20rec,studyType:int%20exp&lat=54.5259614&lng=15.2551187

Studie v Israeli

• clinicaltrials.gov/search?cond=Small%20Cell%20Lung%20Carcinoma&locStr=Israel&distance=50&aggFilters=ages:adult%20older,sex:m,status:not%20rec,studyType:int%20exp&country=Israel