Diagnostika

Laboratory confirmation

• When vesicles are not present
• To rule out other causes of genital ulcers

Direct detection from lesions

• Antigen detection
• Nucleic acid amplification tests (NAATs) for viral DNA
• Isolation of virus by culture
• Previously been considered the gold standard for HSV-2 diagnosis
• NAATs are increasingly preferred due to
• Higher sensitivity
• Ease of specimen collection and transportation
• Faster results [1]

Indirect serological methods

• Serological assays to screen for HSV-2 infection by detection of type-specific antibodies
• Develop in the first several weeks after initial infection
• Persist indefinitely [1]

Klinikcky

• Dle vsikul