nemoci-sympt/VIROLOGIE/nipah/nevi-se

4-Azidocytidine

Trials against Hepatitis C Virus and Dengue Virus

• Halted due to low efficacy and extreme toxicity
• journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007419

ZINC12362922 is a compound known as "Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic

• Mentioned in the context of computational modeling for drug discovery
• Part of research related to therapeutics against certain diseases, such as the Nipah virus.
• journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007419

Cyclopent-1-ene-1,2-dicarboxylic acid

• This compound is known and used in computational modeling for drug discovery against the Nipah virus
• Antiasthmatic and antipsoriatic
• Binds to a pocket of the N protein with RMSD_lig of 0.085 nm.
• journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007419