MUDr. Dana Maňasková


Vyhledávání na medicinman.cz
 

leky-latky/apoa2/funkce

Adipogenesis

  • 265 APOA2 region
  • Possibility of allele-specific binding of the transcription factor CEBPA [CCAAT/enhancer binding protein (C/EBP), alpha]
    • Involved in adipogenesis [5]

Apolipoprotein A-II

  • In humans is encoded by the APOA2 gene
  • Second most abundant protein of the high density lipoprotein particles
  • In plasma as a monomer, homodimer, or heterodimer with apolipoprotein D

Satiety signal

  • APOA2 acts as a satiety signal
    • As described for APOA4 in other studies
      • Significant associations between the APOA2 -265T>C SNP and food intake in Framingham and in GOLDN [5]

Stabilizac eHDL

  • May stabilize HDL (high density lipoprotein) structure
    • By its association with lipids, and affect the HDL metabolism [2]
O úroveň výše

Poslední aktualizace: 11. 12. 2023 23:27:00