leky-latky/pycnogenol/ucinky

Antiastmatický

• Helps fight against hayfever and asthma
• Demonstrated to help asthmatics improve their breathing ability.
• Allows easier breathinig
• Allergens, such as in hay-fever
• Commonly pollen, dust, mite and animal hair.
• histamine in turn triggers sneezing, nasal congestion, coughing, wheezing, itching and bronchial swellings [2]
• Pycnogenol® found to inhibit the release of histamine from mast cells that were aggravated by an irritant
• An anti-inflammatory
• Inhibits production of pro-inflammatory mediators
• Helping to relieve swelling and making breathing easier [2]
• Pycnogenol® also exhibited promise in the management of childhood asthma
• 60 children aged 6 to 18 years with mild to moderate asthma
• Significantly reduce or discontinue their use of rescue inhalers when they supplemented with Pycnogenol®
• Placebo group experienced no benefit [2]

• Pycnogenol improves breathing ability (FEV1) [2]
• Pycnogenol® Reduces Critical Asthma Symptoms In New Clinical Trial read more [2]
• Study Demonstrates The Anti-Inflammatory Properties of Pycnogenol® on Inflammatory Mediators COX-2 [2]

Antidestičkové účinky

• Helps make blood platelets less «sticky»
• Reduce blood clots
• Enhances the body’s own response to counteract blood vessel constriction
• Helps maintain blood pressure that is already in the normal range

Snižuje cholesterol

• Natural option for maintaining healthy cholesterol levels
• Supplementing with Pycnogenol® was found to lower the «bad» (LDL) cholesterol
• Increasing the «good» (HDL) cholesterol [2]

Improves cognitive function

• Studies reveal Pycnogenol® improve both numerical and spatial working memory using a computerized testing system.
• Pycnogenol® was found to improve memory and test scores in college students
• Clinical trial has shown Pycnogenol® to improve mental performance and decrease test anxiety by 17 %
• Several recent research studies on Pycnogenol® studied the extract's effects on Attention Deficit Disorders including ADHD
• Reduce symptoms in children [2]

Significantly delays uptake of complex sugars such as starch

• Potently inhibits the digestive enzyme alpha-glucosidase in the duodenum
• Inhibitors such as green tea extract, pure catechin and the oral medication acarbose (Precose, Glucobay) are dramatically less potent
• Pycnogenol® delays the uptake of glucose from a meal 190 times more potently

Kůže a kolagen

• Pycnogenol® has a high affinity to the amino acid hydroxy-proline
• In matrix proteins collagen and elastin.
• Pycnogenol® (and also its metabolites) protects these proteins from free radical damage and enzymatic degradation.
• Enhanced collagen synthesis with Pycnogenol® in skin of human volunteers
• Increased synthesis of hyaluronic acid in women‘s skin
• Better skin elasticity and water retent
• Pycnogenol® enhances blood micro-circulation in the skin
• Enhances generation of endothelial nitric oxide (NO)
• Key mediator facilitating arterial relaxation and consequently allows for optimal blood flow.
• Pycnogenol® was found to increase blood perfusion of the skin and oxygen partial pressure increased
• Carbon dioxide concentration decreased
• Improved healing of wounds (ulcers) in individuals with micro-circulatory disorders [2]
• Improved skin respiration
• Improve Psoriasis Symptoms Including Redness, Skin [2]
• Improve Visable Signs of Aging [2]

Strengthens retinal capillaries and preserves eye sight

• Pycnogenol® strengthens retinal capillaries
• Helps control leakage of fluids and blood into the retina [2]
• Early stage retinopathy Pycnogenol®
• Stop leakage and improve retinal perfusion
• Corresponding significant restoration of vision [2]
• Five clinical studies
• With over 1000 patients
• Proprietary bilberry extract
• Ingredient combination normalizes intraocular pressure
• Significantly reduces the likelihood of developing glaucoma [1]
• Lutein and Pycnogenol®
• Antioxidant protective effect of the retina
• Combination showed additional synergistic protection of retinal lipids from oxidation [2]

Účinky

• Powerful antioxidant
• Natural anti-inflammatory
• Helps generate collagen and hyaluronic acid
• Aids in the production of endothelial nitric oxide
• Helps to dilate blood vessels [1]

Increasing vasodialation

• Improving blood flow

Proti otokům nohou

• One of the earliest discoveries about the extract was its ability to strengthen capillary walls
• In both pre-clinical and clinical studies to strengthen capillary walls and prevent edema
• Seals the brittle capillaries
• Stops the outflow of blood into tissue which causes the swellings, edema and microbleedings
• Coupled with
• Anti-inflammatory properties
• Reducing platelet aggregation
• Fundamental mechanisms of action behind Pycnogenol® for venous health.

• 15 clinical studies with a total of 784 patients on venous insufficiency and Pycnogenol
• High efficacy of Pycnogenol® as a venous insufficiency treatment was so obvious
• German double-blind comparative study with 40 CVI patients
• Pycnogenol® more effective in a lower dosage in reducing edema of the lower limbs and alleviating the symptoms of CVI than horse chestnut seed extract.

• 70 patients in treating venous insufficiency x troxerutine, a water-soluble derivative of rutine
• After 60 days of treatment
• Combination of troxerutine coupled with Pycnogenol® produced more significant results in alleviating CVI symptoms than troxerutine alone [2]

• One of the more recent clinical studies on swelling found that
• Pycnogenol® can have a positive effect on leg swelling (edema) during long airplane flights lasting 7-12 hours
• In-flight ankle swelling of 169 participants
• Passengers who supplemented with Pycnogenol® experienced less leg and ankle swelling and discomfort [2]

• Study of 211 passengers on a long-distance flight (7-12 hours)
• Ability of Pycnogenol® to help prevent thrombosis:
• Two 100 mg Pycnogenol® capsules 2 - 3 hours prior to departure
• Another two capsules 6 hours later during the flight
• Another capsule was taken the following day after arrival [2]
• Five cases of thrombosis in the control group taking the placebo
• None of the passengers supplementing with Pycnogenol® [2]

• Study Shows Pycnogenol®
• Can Help Improve Endothelial Function in Cases of Borderline Hyperglycemia
• Effective to Naturally Improve Varicose and Spider Veins Following Pregnancy [2]

Zmírnění symptomů menopauzy

• Is demonstrated to be safe
• Does not incur any hormonal alterations in menopausal women
• Defies visible signs of ageing
• Improving skin elasticity
• Smoothness and moisture
• Elevation of collagen, elastin and hyaluronic acid synthase in menopausal women [2]