Zlepšující, podpůrné faktory a terapie
Glossy privet - Ligustrum lucidum
- Reduce side effects of chemotherapy and improve immune function
- Chinese use the fruit of glossy privet to clinically treat leukopenia (Leung & Foster, 1996)
- Khoo and Ang (1995) refuted this practice, finding that glossy privet did not induce any effects on leuko?penia in a study conducted on Wistar rats
- Lau, Ruckle, Botolazzo, and Lui (1994) found that glossy privet fruit had potential to inhibit growth of renal cell carcinoma.
- No adverse reactions are reported for glossy privet
- Common dose is 5-15 g of powdered berries per day (Natural Medicines Comprehensive Database, 2004)
Herbs or Natural Products That Decrease Cancer Growth Part One of a Four-Part Series; Muriel J. Montbriand, PhD, RN; Downloaded on 08 28 2019. Single-user license only. Copyright 2019 by the Oncology Nursing Society. For permission to post online, reprint, adapt, or reuse, please email pubpermissions@ons.org
Alpha-mangostin
The migration and metastasis of A-498 and 786-O renal carcinoma cells were inhibited by ?-mangostin via inhibition of the phosphorylation of ERK but not p38 [40]. This study did not observe any cell toxicity or changes in cell viability in renal carcinoma cells treated with ?-mangostin, which may be explained by the low concentrations tested in this study (>12 µM)Melatonin has a scientific name of N-acetyl-5- methoxytryptamine
- For cancer of the breast, brain, lung, prostate, head, neck, and gastrointes?tinal tract
- Melatonin is also used for jet lag, insomnia, nicotine withdrawal, headache, hypertension, and other conditions.
- Can decrease the incidence of cytokine-induced hypotension for patients with cancer.
- Interleukin-2 and tumor necrosis factor
- Examples of cyto?kines (Lissoni et al., 1996a)
- Quick-release melatonin
- May be beneficial in decreasing potential sleep disorders associated with conditions such as
- Thrombocytopenia induced by chemotherapy or interleukin-2 (Bregani et al., 1995; Micromedex Healthcare Series, 2003; Lissoni et al., 1995, 1996b, 1999).
- Beneficial in stabilizing disease for adults with solid tumors who do not respond to treatments or cannot receive treatments (Micromedex Healthcare Series; Lissoni et al., 1991, 1994a).
Herbs or Natural Products That Decrease Cancer Growth Part One of a Four-Part Series; Muriel J. Montbriand, PhD, RN; Downloaded on 08 28 2019. Single-user license only. Copyright 2019 by the Oncology Nursing Society. For permission to post online, reprint, adapt, or reuse, please email pubpermissions@ons.org
Melatonin + interleukin-2
- Seems to improve survival for patients with advanced solid tumors of the breast, gastrointestinal tract, kidney, liver, and lung and melanoma
Melatonin + triptorelin pamoate
- For prostate cancer, radiotherapy for glioblastoma
Micromedex
- melatonin + interferon for renal cell cancer (Micromedex Healthcare Series).
Adverse effects of melatonin
- Headaches, transient depression,
- Daytime fatigue and drowsiness,
- Dizziness, abdominal cramps,
- Irritability (Micromedex Healthcare Series, 2003; Wagner, Wagner, & Hening, 1998)
- Reduces alertness (Dollins et al., 1993, Micromedex Healthcare Series)
- Commercially available melatonin usually is synthesized in laboratories
- Possible contamination
- Optimal safe dose has not been established
- 20-50 mg along with radiation or chemotherapy has been used for cancer treatment (Brzezinski, 1997; Micromedex Healthcare Series, 2003).
Herbs or Natural Products That Decrease Cancer Growth Part One of a Four-Part Series; Muriel J. Montbriand, PhD, RN; Downloaded on 08 28 2019. Single-user license only. Copyright 2019 by the Oncology Nursing Society. For permission to post online, reprint, adapt, or reuse, please email pubpermissions@ons.org
- Quercetin and quercetin-3-O-galactoside in equal proportion
- Downregulated the oncogenic miRNA-27a in 786-O renal cancer cells
