Spray do nosu

Spray / nosní kapky s antivirotickými účinky

pH values of 5.0

• Known to reduce Rhinovirus infectivity [1]

Ascorbic acid

• Or its salts
• In presence of oxygen and heavy metal ions [1]
• Known to reduce Rhinovirus infectivity [1]

Glutaric acid [1]

• Known to reduce Rhinovirus infectivity [1]

NaCl výplachy

• Known to reduce Rhinovirus infectivity [1]

Pyroglutamic acid

• And an organic acid
• PKa value 3.0 - 5.0 [1]
• ascorbic acid [1]
• Known to reduce Rhinovirus infectivity [1]

Mono-, di-, tri- carboxylic acids [1]

• Known to reduce Rhinovirus infectivity [1]
• Salicylic (součástí mnoha ovoce)
• Fumaric
• benzoic
• Glutaric
• Lactic
• Citric
• Malonic
• Acetic (ocet)
• Glycolic
• Malic (v jablku)
• Adipic
• Succinic
• Aspartic
• Phthalic
• Tartaric
• Glutamic
• Gluconic [1]

Chelating Agents

• Enhance antiviral activity
• By denying the virus metal ions
• Chelate
• Iron
• copper
• Zinc
• Silver etc.

Zinc ions - Zinc acetate

• Antiviral properties of ions itself
• Most preferred metal compound [2]
• Antiviral and antibacterial
• Inhibit cleavage of rhinovirus polypeptides
• Preventing replication and formation of infective virions [1]
• Reduce the ability of rhinoviruses to penetrate cell membranes
• Lowering expression of intercellular adhesion molecule ICAM. [1]
• Stimulate
• T-cell lyphocytes
• Interferon-gamma
• Stabilize cell plasma membranes
• Protecting cells from cytotoxic agents
• Preventing cell leakage [1]

Phytic acid

Disodium and calcium salts of ethylene diamine tetraacetic acid (EDTA)

Tetrasodium EDTA [1]

Sodium hexametaphosphate (SHMP)

Di(hydroxyethyl)glycine

8-hydroxyquinoline [1]

Lokální antivirotika

• Amantidine
• Rimantidine
• Pleconaril
• Zanamivir
• Oseltamivir [3]